- 期刊
幽門螺旋桿菌感染與中醫證型的相關性研究
The Correlations between the Helicobacter pylori Infection and the Diagnostic Patterns of Traditional Chinese Medicine
摘要
目的：利用統計方法找出中醫證型與幽門螺旋桿菌感染的相關性，及除菌療法後中醫證型與幽門螺旋桿菌感染的關聯。方法：亞東紀念醫院因消化性潰瘍或胃炎由醫師安排做碳－13尿素呼氣試驗者，共298例。其中幽門螺旋桿菌陰性223例，陽性66例，邊緣性9例；半年內因幽門螺旋桿菌感染接受過除菌療法的有145例。自設中醫診斷標準分虛、實、寒、熱證型，與幽門螺旋桿菌陰性及陽性病例以卡方檢定、對數迴歸等統計方法找出其相關性。結果：所有幽門螺旋桿菌陽性及陰性病例，與虛實辨證、寒熱辨證、虛實寒熱混合辨證、食後較痛、脹、惡冷或喜熱、口苦或口臭等變數有相關。其中證型以寒熱辨證最有相關，寒熱夾雜型之幽門螺旋桿菌陽性的機率是寒證的3倍。接受除菌療法者，幽門螺旋桿菌感染與虛實辨證、寒熱辨證、虛實寒熱混合辨證、脹、惡冷或喜熱、大便乾燥、質裂等變數有相關。其中證型以寒熱辨證最有相關，寒熱夾雜型之幽門螺旋桿菌陽性的機率是寒證的5.9倍。結論：幽門螺旋桿菌感染和中醫虛實寒熱辨證有相關，幽門螺旋桿菌陰性較陽性易出現虛寒證，幽門螺旋桿菌陽性較陰性易出現虛實寒熱夾雜型，尤其是接受過除菌療法的病例更為顯著。其中又以寒熱辨證最有相關，寒熱夾雜型幽門螺旋桿菌陽性機率較寒證高。因此除菌療法後，如果病人為寒證，幽門螺旋桿菌陰性的機率較高；如果病人為寒熱夾雜型，幽門螺旋桿菌陽性的機率較高。
並列摘要
Objective: To find the correlations between the Helicobacter pylori (HP) infection and diagnostic patterns of traditional Chinese medicine.Design: A cross-sectional observation study.Setting: Far Eastern Memorial Hospital.Patients: 298 patients with peptic ulcer or gastritis including 145 eradicated persons.Measurements: 13C-urea breath test and pattern identifications including vacuity, repletion, cold, and heat.Results and Conclusions: HP infection is correlated with the pattern identifications. Negative HP has the higher rate of vacuity-cold pattern and positive HP has the higher rate of vacuity-repletion-cold-heat mixed pattern. They are more significant in the eradicated patients. The cold-heat identification is the most significant. The cold-heat mixed pattern has the higher rate of positive HP than the cold pattern. So in the eradicated patients, if cold pattern was identified, the HP has the higher rate to be negative. Whereas if cold-heat mixed pattern was identified, the HP has the higher rate to be positive.