Flow separation is identified as the primary cause of compressor inefficiency. To enhance performance and mitigate flow separation, boundary layer suction was implemented in axial compressor cascades. The two types of suction, combined and suction surface, were studied. The effects of size, position, and flow rate on the performance and flow field were also studied. The findings indicated that enhancing the suction flow rate can lead to a decrease in losses. The mid-span and all-span suction schemes can help minimize the end wall loss. On the other hand, the suction slot situated upstream has a higher loss. For controlling the flow separation, the loss of combined suction is 60.06% lower than the baseline cascade. The flow mechanism is that boundary layer separation can be reduced by the suction surface suction; the corner separation and low-momentum flow induced by secondary flow can be minimized by end wall suction. The suggested axial location of end wall suction slot should locate downstream of the intersection position between the suction surface branch of the horseshoe vortex and the suction surface in the cascade. This area corresponds to the formation and development stage of the three-dimensional corner separation region. Therefore, the end wall suction can effectively absorb a large number of low-energy fluids. The suggested circumferential location of end wall suction slot should be near suction surface, because the control effectiveness of combined suction on the corner separation is reduced when the end wall suction slot moves away from the suction surface.