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Granulomatous Prostatitis Mimicking Malignancy on F-18 FDG PET/CT in a Patient with Urinary Bladder Cancer after Bacillus Calmette-Guerin Therapy: A Case Report and Literature Review

膀胱癌患者接受卡介苗灌注治療後之肉芽腫性攝護腺癌在氟化去氧葡萄糖正子造影中表現仿似惡性腫瘤:病例報告及文獻回顧

摘要


Granulomatous prostatitis is a potential complication of intravesical bacillus Calmette-Guerin (BCG) immunotherapy for urinary bladder cancer and may affect interpretation of fluorine-18-fuorodeoxyglucose positron emission tomography and computed tomography (F-18 FDG PET/CT) as suggested by only a few case reports in the literature. We reported a 79-year-old male patient with a history of urinary bladder urothelial carcinoma post transurethral resection of bladder tumor (TURBT) and intravesical BCG therapy. The post-therapy F-18 FDG PET/ CT showed a remarkable hypermetabolic lesion in the prostate gland and malignancy was suspected by both F-18 FDG PET/CT and transrectal ultrasonography (TRUS). Biopsy of the prostate gland revealed granulomatous inflammation without evidence of malignancy. The follow-up F-18 FDG PET/CT showed remarkable regression of the hypermetabolic lesion.

並列摘要


肉芽腫性攝護腺炎是一種膀胱癌卡介苗灌注免疫治療後的併發症,並會影響影像檢查判讀。目前確診並記載氟化去氧葡萄糖正子影像的案例並不多。本案例報告一位79 歲男性膀胱癌患者,接受膀胱腫瘤切除手術以及卡介苗灌注治療後,首次接受氟化去氧葡萄糖正子造影時,在攝護腺發現一明顯高代謝局部病灶,正子造影與經直腸超音波檢查皆懷疑其為惡性,病理切片診斷為肉芽腫性攝護腺炎、並非惡性腫瘤,後續正子造影追蹤顯示原病灶之氟化去氧葡萄糖攝取明顯降低。

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