Tc-99m-ECD SPECT Analyzed by Easy Z-Score Imaging System Enhancing the Early Diagnosis of Logopenic Progressive Aphasia

eZIS分析鎝－99m ECD單光子斷層在少詞型進行性失語症早期診斷的幫助

楊聖功(Sheng-Kung Yang) ； 魏誠佑(Cheng-Yu Wei) ； 侯柏年(Po-Nien Hou) ； 謝元昌(Yuan-Chang Hsieh) ； 蔡文凱(Kevin Wen-Kai Tsai) ； 邱百誼(Pai-Yi Chiu) ； 洪光威(Guang-Uei Hung)

《核子醫學暨分子影像雜誌》 31卷4期 (2018/12) Pp. 224-229

https://doi.org/10.6332/ANMMI.201812_31(4).0005

摘要

A 76-year-old male with cognitive impairment was initially impressed as an early Alzheimer's disease (AD). Tc-99m-ECD brain single photon emission computed tomography (SPECT) was arranged for further evaluation and conventional display showed focal hypoperfusion in left temporal and parietal lobes. Statistical analysis with easy Z-score imaging system (eZIS) showed a typical picture of logopenic progressive aphasia (LPA). During the following 12-month period, rapid deterioration of language function was noted, especially the naming and sentence repetition. Further language function examination confirmed the final diagnosis of LPA.

關鍵字

cerebral perfusion ； eZIS ； logopenic progressive aphasia ； SPECT

並列摘要

76歲男性原診斷早期阿茲海默症，腦灌注單光子斷層掃描可見左側顳葉與頂葉有低灌注異常，easy Z-score imaging system (eZIS)軟體軟體分析為典型的少詞型進行性失語症影像特徵。經12個月的追蹤，其語言功能快速退化，語言功能檢查顯示在命名和句子重覆兩方面有明顯異常，確診為少詞型進行性失語症。

並列關鍵字

腦灌注 ； eZIS ； 少詞型進行性失語症 ； 單光子斷層掃描