Background: Eczema herpeticum is an uncommon manifestation of an infection with herpes simplex virus (HSV). The disease is primarily seen in patients with histories of atopie eczema. Eczema herpetieum may be a life-threatening illness, but the mortality is felt to be <10% with modern antiviral and antibacterial agents. The use of aeyelovir for other viral infections secondary to herpesvirus in pregnancy has been well documented. The authors now present a ease report of eczema herpetieum treated with aeyelovir during pregnancy. Case: A patient with a history of eczema herpetieum presented in pregnancy with a recurrence. She was successfully treated with intravenous (IV) aeyelovir with good maternal and fetal outcome. Conclusion: Aeyelovir may be utilized in pregnancy for several manifestations of HSV including eczema herpetieum.