- 期刊
Associations between P3 Responses and Continuous Performance Test in Children with Attention Deficit Hyperactivity Disorder and Typically Developing Children
探討過動兒和典型發展兒童的P3反應與持續性表現作業之關聯
摘要
Objective: To investigate the associations between P3 responses induced by a Go/NoGo task and behavioral performance measured by the Continuous Performance Test (CPT) in children with attention deficit hyperactivity disorder (ADHD) and typically developing (TD) children. Methods: The sample consisted of 21 children with ADHD and 20 TD children. All participants performed two neuropsychological tasks (i.e., Go/NoGo task and CPT), the order of which were randomly assigned. Electrophysiological data were recorded while participants were performing the Go/NoGo task. Behavioral variables (i.e., omission errors, commission errors, reaction time [RT], and reaction time standard errors [RTSE]) measured by the CPT and event-related potentials (i.e., P3 latencies and amplitudes at electrode sites-Fz, Cz, and Pz) evoked by the Go stimuli were collected. Correlations between behavioral variables and P3 responses were calculated. Results: Regarding the correlations between P3 responses and CPT performance, different patterns were observed between groups. For children with ADHD, significant associations were found between P3 latencies at Fz and RTs (r = .493, p ＜ .05), P3 latencies at Cz and RTs (r = .566, p ＜ .01), and P3 latencies at Cz and RTSEs (r = .524, p ＜ .05). For TD children, significant associations existed between P3 latencies at Fz and omission errors (r = -.584, p ＜ .01), P3 latencies at Fz and RTSEs (r = -.601, p ＜ .01), and P3 latencies at Cz and RTSEs (r = -.444, p ＜ .05). Conclusion: The results indicate that some different mechanisms may be involved when children with ADHD and TD children perform the neuropsychological tasks. However, future studies with larger sample sizes are warranted to validate the current findings.
並列摘要
目的：探討注意力不足過動症兒童（過動兒）和典型發展兒童在執行Go/NoGo作業時所誘發的P3反應與在持續性表現作業（Continuous Performance Test; CPT）上的行為表現之相關性。方法：21位過動兒及20位典型發展兒童接受兩個神經心理學作業（即Go/NoGo作業和持續性表現作業）的施測，作業的施測次序是隨機安排。當受試者在執行Go/NoGo作業時，其電生理的訊號會被記錄。本研究中，我們收集由持續性表現作業所測量的行為變項（即遺漏錯誤、替代性錯誤、反應時間以及反應時間標準誤）和由Go刺激所誘發的事件相關電位（即在Fz、Cz及Pz的P3振幅及潛伏期）。進一步地，我們計算P3反應和行為變項的相關性。結果：P3反應和由持續性表現作業所量測的行為表現之間的相關在組別間呈現不同的結果。對於過動兒，顯著的相關呈現在Fz的P3潛伏期和反應時間（r=.493, p＜.05），Cz的P3潛伏期和反應時間（r=.566, p＜.01），Cz的P3潛伏期和反應時間標準誤（r=.524, p＜.05）。對於典型發展兒童，顯著的相關存在於Fz的P3潛伏期和遺漏錯誤（r=-.584, p＜.01），Fz的P3潛伏期和反應時間標準誤（r=-.601, p＜.01），Cz的P3潛伏期和反應時間標準誤（r=-.444, p＜.05）。結論：結果顯示過動兒和典型發展的兒童在執行神經心理學作業時可能運用不同的機制。然而，未來需要有較大樣本的研究來證實此研究的結果。