This paper briefly reviews two-dimensional gel electrophoresis ( 2-DGE) and capillary electrophoresis (CE) for proteomics. 2-DGE provides capability of resolving thousands of proteins in a gel, while it is tedious, time-consuming, in sensitive, and not easy for automation. On the other hand, CE in conjunction with laser-induced fluorescence ( LIF ) or with mass spectrometry ( MS) is advantageous over 2-DGE, including rapidity, sensitivity, and ease for automation, but provides relatively low resolving power. It is thus our belief that techniques combined with electroelution, CE, 2-DGE, LIF, and MS will be suitable for proteomics.