Subendocardial Fibrosis in Left Ventricular Hypertrabeculation-Cause or Consequence?

J. Ker ； L. Du Toit-Prinsloo ； W. F. P. Van Heerden ； G. Saayman

《Clinical Medicine Insights: Cardiology》 2011卷 (2011/12) Pp. 13-16

https://doi.org/10.4137/CMC.S6507

並列摘要

Left ventricular noncompaction has been classified as a primary cardiomyopathy with a genetic origin. This condition is morphologically characterized by a thickened, two-layered myocardium with numerous prominent trabeculations and deep, intertrabecular recesses. Recently, it has become clear that these pathological characteristics extend across a continuum with left ventricular hypertrabeculation at one end of the spectrum. The histological findings include areas of interstitial fibrosis. We present a case of left ventricular hypertrabeculation which presented as sudden infant death syndrome. Histologically areas of subendocardial fibrosis was prominent and we propose that this entity may be a hidden cause of arrhythmic death in some infants presenting as sudden infant death syndrome., with areas of subendocardial fibrosis as possible arrhythmogenic foci.

並列關鍵字

sudden infant death syndrome ； hypertrabeculation ； noncompaction ； fibrosis