摘要
前縱膈腔是最常見的生殖腺外生殖細胞瘤(extragonodal germ cell tumor, EGCTs) 原發部位。臨床症狀可能有胸悶、咳嗽、喘、阻塞性肺炎、體重減輕、上腔靜脈症候群、發燒、噁心等。依據細胞型態及分泌之腫瘤指標又可分為精原性(seminomataous, germinomatous)和非精原性(non-seminomatous ) 。治療依據腫瘤分型有所不同，以手術切除及化學治療為主，輔以放射治療、血液幹細胞移植等。本病例為一位37歲男性，經確診前縱膈腔精原細胞瘤後，接受化學治療及局部放射治療。
參考文獻
Bokemeyer C, Nichols CR, Droz JP, et al. Extragonadal germ cell tumors of the mediastinum and retroperitoneum: results from an international analysis. J Clin Oncol 2002;20:1864-73."
Rusner C, Trabert B, Katalinic A, et al. Incidence patterns and trends of gonadal and extragonadal germ cell tumors in Germany, 1998-2008. Cancer Epidemiol 2013;37:370-3."
Gilligan TD, Seidenfeld J, Basch EM, et al. American Society of Clinical Oncology Clinical Practice Guideline on uses of serum tumor markers in adult males with germ cell tumors. J Clin Oncol 2010;28:3388-404."
Samuels ML, Johnson DE, Holoye PY, et al. Large-dose bleomycin therapy and pulmonary toxicity. A possible role of prior radiotherapy. JAMA 1976; 235:1117-20."
Motzer R, Bosl G, Heelan R, et al. Residual mass: an indication for further therapy in patients with advanced seminoma following systemic chemotherapy. J Clin Oncol 1987;5:1064-70."
被引用紀錄
王偉靜、楊淑慧（2023）。一位縱膈腔卵黃囊瘤末期青年之護理經驗。志為護理-慈濟護理雜誌，22(2)，87-95。https://www.airitilibrary.com/Article/Detail?DocID=16831624-N202305230009-00021