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摘要


圍術期過敏性休克(anaphylaxis)是一個可能危及生命的臨床狀況,且常是由麻醉或手術時使用的藥物或特定物質導致。由於目前仍不存在針對過敏的預先治療,因此在過敏反應發生後,必須藉由過敏學的相關試驗來確認過敏原,並避免再次發生。本篇文章回顧了以下幾點:1.過敏之生理機制與症狀;2.麻醉過程中導致過敏反應之常見過敏原;3.針對過敏性休克之適當處置與治療。

參考文獻


1. Butterworth JF, Mackey DC, Wasnick JD. Morgan & Mikhail's Clinical Anesthesiology, 6th ed. New York, NY: McGraw-Hill, 2018:1246-51.
2. Dewachter P, Mouton-Faivre C, Emala CW. Anaphylaxis and Anesthesia: Controversies and New Insights. Anesthesiology 2009;111:1141-50.
3. Kroigaard M, Garvey LH, Gillberg L, et al. Scandinavian Clinical Practice Guidelines on the diagnosis, management and follow-up of anaphylaxis during anaesthesia. Acta Anaesthesiol Scand 2007;51:655-70.
4. Harper NJ, Dixon T, Dugue P, et al. Suspected anaphylactic reactions associated with anaesthesia. Anaesthesia 2009;64:99-211.
5. Simons KJ, Simons FE. Epinephrine and its use in anaphylaxis: current issues. Curr Opin Allergy Clin Immunol 2010;10:354.

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