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脈衝式治療於類固醇抗性免疫性肺炎的應用

摘要


免疫治療已經成為許多癌症的標準治療之一,然而,部分患者會發生中重度的免疫相關副作用,高劑量類固醇為目前建議的第一線用藥,但有少數的患者會發生類固醇抗性的免疫相關副作用。現行治療指引對此建議其他免疫抑制劑的使用,但最佳的用藥選擇目前尚無共識。本文提出一位晚期肝癌患者接受免疫治療後引起類固醇抗性的免疫性肺炎,並進展至急性呼吸窘迫症候群。經脈衝式類固醇治療後,肺炎得到完全緩解且順利脫離呼吸器出院。

參考文獻


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