Since the 5th century BCE, apophatic theology has been constructed as a theological system which stresses that God cannot be known in terms of human categories. Due to its critical nature, negation theology exists as a disciplinary which requires constant questioning of religious claims. Via Negativa then is an important method in religious dialogue. On the one hand, it eliminates the extreme form of religious exclusivism; on the other hand, it brings religions to self-transformation and liberation. This paper attempts to apply to the Via Negative Buddhist concept of emptiness so as to show the effectiveness of this method in religious dialogue.