- 期刊
Comparison of Sevoflurane with Halothane in Pediatric Ambulatory Anesthesia: An Experience in Taiwan
兒科門診手術Sevoflurane與Halothane麻醉之比較：台灣經驗
摘要
Background: Sevoflurane, with blood/gas partition coefficient of 0.69 and MAC of 1.76 is a fast acting, potent inhalational anesthetic. Its suitability and safety for pediatric ambulatory anesthesia were assessed and compared with that of halothane. Methods: Thirty two unpremedicated pediatric patients undergoing elective herniorrhaphy on day-surgery basis were randomly allocated to 2 groups of equal number to receive either sevoflurane or halothane anesthesia. Employing mask technique, anesthesia was induced with 60% nitrous oxide and 3 MAC of either sevoflurane or halothane in oxygen. Anesthesia was maintained respectively with 1-1.5 MAC of sevoflurane or halothane. The induction time, emergence time and untoward effects during anesthesia were analyzed and compared. Results: It was shown that both the induction time and emergence time were significantly shorter in patients receiving sevoflurane. None had major complications. Conclusions: The results strongly suggest that sevoflurane is preferable to halothane for pediatric ambulatory anesthesia.
並列摘要
背景：Sevoflurane具有血／氣分割系數0.69及最低肺泡濃度MAC1.76的特性，該是一快速作用之吸入性麻醉藥。此篇報告乃是針對sevoflurane與halothane在兒科門診手術麻醉的適應性及安全性作比較。方法：三十二位兒科門診常規疝氣手術兒童被隨意分配成相同人數接受sevoflurane或halothane麻醉。60%笑氣加相關吸入性麻醉藥在氧氣之下作誘導麻醉，麻醉藥維持在1.0－1.5 MAC之下，手術在平穩中完成。經分析兩組麻醉誘導時間、甦醒時間及併發症。結果：結果顯示在sevoflurane組，誘導及甦醒時間都比較快速，兩組都沒有發生重大併發症。結論：Sevoflurane比halothane更合宜使用在兒科門診手術麻醉。