- 期刊
電腦斷層顯影劑對於不良反應之探討
Contrast Medium used for Computerized Tomography Examination and Adverse Event
摘要
於2011年2月後，健保局全面給付電腦斷層之非離子顯影劑，雖然非離子顯影劑能降低不良反應的發生率，但還是會有發生的風險存在，這是臨床上需要去注意。本研究主要分析電腦斷層使用的兩種顯影劑，收集2011年2月至2015年12月因檢查施打優照維斯（Ultravist-300）和安你拍克（Omnipaque-350）進行研究與分析。利用羅吉斯回歸分析，性別、年齡層、顯影劑廠牌與注射的劑量與不良反應之發生是否有相關性。結果顯示造成不良反應共有74人次，安你拍克顯影劑有18人次，優照維斯有56人次。其中顯影劑廠牌與不良反應發生具有顯著關連性（P＜0.001），施打優照維斯顯影劑造成過不良反應的風險為施打安你拍克顯影劑的3.25倍。爾後，對於海鮮、貝類與藥物有過敏體質之患者，可以選擇安你拍克顯影劑，依據本研究結果顯示可降低不良反應的發生，作為臨床之參考。
並列摘要
After February 2011, non-ionic contrast media is covered by Health Insurance. Although, non-ionic contrast media can reduce the incidence of adverse event, but there will still be the risk of existence. This is a clinical need to pay attention. This study focuses on the analysis of two types of contrast media (Ultravist-300 and Omnipaque-350) used in computerized tomography, which were collected and analyzed from February 2011 to December 2015. Using Logistic regression analysis, whether there is a significant difference in adverse event. The results showed that there were 74 adverse events, Omnipaque-350 have 18 people, Ultravist-300 have 56 people. There was a significant difference between adverse event and types of contrast media (P＜0.001). Ultravist-300 is 3.25 times the risk of Omnipaque-350. Later, for seafood, shellfish and drugs in patients with allergies, you can choose Omnipaque-350, based on the results of this study showed that adverse event can be reduced, as a clinical reference.