3D printing technologies can be used for food fabrication to achieve many goals such as providing novelty and fun, convenient and efficiency, healthy nutrition, reducing waste and enhancing sustainable environment. However, the lack of printable materials, product varieties, low printing accuracy and low productivity are still the main challenges. In addition, the structure design, sensory quality and nutritional value also need to be strengthened to improve the acceptance of 3D food printing technologies by the public. Through the development of health and safety regulations compliance for 3D printing equipment that are suitable for food fabrication and integrated with material discharge, environmental control, product formulation rheology, printing and post-processing conditions, the 3D food printing can then create sticky, filled, gel and foam structured nutritional leisure food, veggie meat, food for elderly people and meet the concept of clean labeling.