In this study, we aim at exploring the relationship between Four Pillars of Destiny (子平八字)and college student's academic performance. Our sample consists of 60 college students from a university located in Taichung area. We computed several variables and compound variables to predict students' academic performance. Our results showed that Shan Guan is negatively associated with students' academic performance. In addition, compound variables, such as Shin Shan Sheng Cai (食傷生財) and Shi Shen Zhi Sha (食神制殺), are all positively associated with students' academic performance. This study also implied that university administrators could use Zi Ping Ba Zi as basic models to assist students' learning progress. The theoretical and practical implications of our findings are also discussed.