- 期刊
辛夷、艾葉、黃柏、當歸與陳皮等本草精油對皮膚細胞與黑色素細胞瘤的生長影響
Effects of Magnolia, Artemisia leaf, Philodendron, Angelica and Citrus Essential Oil on Skin Cells and Melanoma
摘要
精油對於腫瘤生長的影響被廣泛討論，並有可能成為有效且無害的補充和替代藥物。各種皮膚細胞在保護身體與修復損傷扮演著重要的角色，如：纖維母細胞(fibroblasts)、角質細胞(keratinocytes)、黑色素細胞(melanocytes)等，我們將辛夷精油、艾葉精油、黃柏精油、當歸精油與陳皮精油混合相對應之細胞培養液後進行人類皮膚細胞與腫瘤細胞培養實驗，以了解並推估精油對抗腫瘤的影響。結果證實五種辛夷精油、艾葉精油、黃柏精油、當歸精油與陳皮精油培養不同種類之細胞，除可抑制皮膚細胞之增殖效率外，還顯著抑制黑色素細胞瘤。因此推估此五種中草藥精油有抗腫瘤的功效，其中辛夷、艾葉、黃柏、當歸精油還對纖維母細胞有顯著抑制作用。
並列摘要
The effect of essential oils on tumor growth is widely discussed and may be an effective and harmless supplement and alternative drug. Various skin cells play an important role in protecting the body and repairing injuries, such as: fibroblasts, keratinocytes, melanocytes. We use Magnolia essential oil, Artemisia leaf oil, Philodendron essential oil, Angelica essential oil and Citrus essential oil for human skin cells and tumor cell culture experiments were performed after mixing the cells and culture medium with these essential oils to understand and estimate the effect of the essential oils on the tumor. The results confirmed that the five species essential oils cultured in different types of cells, in addition to inhibiting the proliferation of skin cells, but also significantly inhibit melanoma. Therefore, it is estimated that the five Chinese herbal essential oils have anti-tumor efficacy. Among them, Magnolia, Artemisia leaf, Philodendron and Angelica essential oils also had significant inhibitory effects on fibroblasts.