Background: Self-study ability is one of the most important factors which affects the quality of each student in higher-education, especially in credit training. Currently, with the rapid development of Internet, students have more opportunities to access more learning materials. Hence, improvement of self-learning via the Internet is necessary. This research describes public health student regarding to the self-learning ability via the Internet and some related factors. Method: A cross-sectional study on 430 public health students at Hue university of Medicine and Pharmacy. Results: The average self-learning time via the Internet is 1.5±1.0 (hours / day), average internet usage is 5.3±2.5 (hours / day) and average self-study time is 3.0±1.5 (hours / day). Students assess their self-directed learning skills on the Internet at the average (3.09/5.00) and assess the faculty's interest in instruction these skills are below average (2.92/5.00). Some related factors are grade, internet usage, impacting from the others, soft skills: concentration, self-awareness, language. Conclusion: 21.6% of students in the Faculty of Public Health, Hue University of Medicine and Pharmacy applied self-learning via the Internet effectively. The average self-study via the Internet is 1.5±1.0 (hours/day), occupied 30±20% the total Internet usage and 51±25% the total self-study time. Some factors relating to the self-study ability via the Internet of students are: grade, self-study maintenance, internet access facilities, and teacher guidance for students on soft skills.