- 期刊
Research Progress in the Diagnosis and Treatment of Liver Cirrhosis
摘要
Liver cirrhosis is caused by one or more reasons. It is a progressive chronic liver disease characterized by diffuse fibrosis, pseudolobule and regenerative nodule of liver tissue. It can lead to severe complications such as upper gastrointestinal hemorrhage, hepatic encephalopathy, secondary infection, canceration and so on, which seriously affects people's health and life. Treatment and reversion of liver fibrosis has always been the goal of scholars all over the world. This paper summarizes many related literature and research in recent years, and reviews the clinical causes and treatment of liver cirrhosis, so as to open up a new way for the treatment of patients with liver cirrhosis.
參考文獻
Trautwein C, Friedman SL, Schuppan D, Pinzani M. Hepatic fibrosis: Concept to treatment. J Hepatol. 2015. 62(1 Suppl): S15-24.
Santoro R, Mangia A. Progress in promising anti-fibrotic therapies. Expert Rev Gastroenterol Hepatol. 2019.
Hernandez-Gea V, Friedman SL. Pathogenesis of liver fibrosis. Annu Rev Pathol. 2011. 6: 425-56.
Spengler U. Hepatic microcirculation: a critical but neglected factor for the outcome of viral hepatitis. J Hepatol. 2009. 50(3): 631-3.
Shimoda S, Tsuneyama K, Kikuchi K, et al. The role of natural killer (NK) and NK T cells in the loss of tolerance in murine primary biliary cirrhosis. Clin Exp Immunol. 2012. 168(3): 279-84.