The aesthetic thought of "emptiness" of Zen has a profound influence on modern graphic design. The most outstanding aesthetic feature of Zen"emptiness" is blank space. In graphic design, through some blank space, it gives people a kind of imaginary tension. Appropriate "emptiness" can not only make the main body outstanding, but also create a sense of hierarchy, space and three-dimensional design. In this paper, through the brief introduction of Zen"empty" concept and appreciation of graphic designer works in China and Japan, the author analyzes the artistic beauty of Zen"empty" concept and the application of blank thought in graphic design.