With the development of the economy and the continuous improvement of the cultural level of consumers, national culture has gradually entered our lives, and cultural and creative products have become more and more sought after, and have become a new type of industry in my country with broad market prospects. In this paper, the characteristics of graphic design, the definition of museum cultural and creative products and their development stages are discussed. On this basis, taking the cultural and creative works of the Palace Museum as an example, the application of graphic design in the design of museum cultural and creative products is proposed.