- 期刊
急性缺血性腦中風使用Tirofiban之新證據
Application of Tirofiban in Acute Ischemic Stroke
並列摘要
This review explores the emerging role of tirofiban, a potent intravenous antiplatelet agent, in the management of acute ischemic stroke (AIS). Tirofiban, a glycoprotein IIb/IIIa inhibitor, has garnered attention for its potential application beyond acute coronary syndrome. The review delves into tirofiban's mechanisms of action and critically analyzes the existing body of evidence from clinical studies, elucidating the efficacy and safety profile of tirofiban in AIS patients. Importantly, recent randomized controlled trials have suggested the application of tirofiban in patients who underwent endovascular thrombectomy (RESCUE BT trial) as well as those without large vessel occlusion stroke but at high risk of deterioration (RESCUE BT 2 trial). By synthesizing existing evidence, tirofiban may offer a novel therapeutic avenue for the management of AIS.