- 期刊
Research Progress of Bioflavonoids and Their Anticancer Activities
摘要
Flavonoids are the main components and active ingredients of many important Chinese herbal medicines. Flavonoids are important natural active compounds, which widely exist in the plant kingdom and have a wide variety, and most of the active flavonoids have broad-spectrum activity, low toxicity and high efficiency. Flavonoids are the internal signal molecules and metabolites of plants, belonging to polyphenols. They have the characteristics of various kinds, complex structures, broad-spectrum pharmacological activities and low toxicity, and have extensive significance for the treatment and prevention of cardiovascular and tumor diseases. Flavonoids are secondary metabolites of plants, which have many biological activities, such as anti-oxidation, anti-angiogenesis, anti-inflammation, anti-virus, hypoglycemic, hypolipidemic and anti-osteoporosis. They are widely distributed in vegetables, fruits and other plants. Studies have shown that dietary intake of rich flavonoids will reduce the risk of cancer such as colon cancer, prostate cancer and breast cancer. Therefore, in recent years, the antitumor activity and mechanism of flavonoids have become a research hotspot. Pharmacological studies have proved that these compounds have obvious inhibitory effects on a variety of human tumors.