Taking the pile foundation design and construction of a project in Pudong New Area of Shanghai as an example, the principle and feasibility of T-PHC bamboo pile as a Pile foundation in coastal soft soil areas are verified through the analysis of geological conditions. Based on the actual situation of the project, the main process parameters, construction process and applicable conditions, as well as some problems encountered during the construction process and solutions and prevention methods are introduced. As the foundation of the underground reservoir is located in the original river channel and adjacent to the newly opened river channel, T-PHC bamboo joint piles have good uplift resistance and bearing capacity, meet relevant requirements and have high economic efficiency.