Imidazolium Ionic Liquid Functionalized Eu^(3+)-ZIF Rapidly and Sensitively Detects Lysine

Jiji Xia ； Shoushang Lian ； Wenxuan Fan

《International Core Journal of Engineering》 10卷6期 (2024/06) Pp. 26-34

https://doi.org/10.6919/ICJE.202406_10(6).0004

摘要

An eco-friendly and green rare-earth hybrid material, Eu^(3+)-ZIF@IL, was synthesized using ionic liquids as a medium through a straightforward hydrothermal method. This material maintains the inherent stability and high porosity of ZIFs while enhancing fluorescence detection capabilities via the integration of ionic liquids. This innovation has yielded a probe with superior fluorescent properties, making it especially effective for the recognition and detection of biomolecules. In practical applications, Eu^(3+)-ZIF@IL exhibits high selectivity and sensitivity towards lysine, achieving effective analysis in complex biological matrices with a detection limit as low as 26.42 μM. This demonstrates its outstanding performance and significant potential in the market for fluorescent probes.

關鍵字

Ionic Liquid ； Rare Earth Hybrid Probe ； Sensing Detection ； Zeolitic Imidazolate Framework ； Lysine

參考文獻

Hafenbradl D, Keller M, Wächtershäuser G, et al. Primordial amino acids by reductive amination of α-oxo acids in conjunction with the oxidative formation of pyrite [J]. Tetrahedron letters, 1995, 36(29): 5179-5182.

Noguchi Y, Zhang Q-W, Sugimoto T, et al. Network analysis of plasma and tissue amino acids and the generation of an amino index for potential diagnostic use [J]. The American Journal of Clinical Nutrition, 2006, 83(2): 513S-519S.

Li T, Ning N, Li B, et al. Longitudinal metabolomics reveals ornithine cycle dysregulation correlates with inflammation and coagulation in COVID-19 severe patients [J]. Frontiers in Microbiology, 2021, 12: 723818.

Abdulbagi M, Wang L, Siddig O, et al. d-Amino acids and d-amino acid-containing peptides: potential disease biomarkers and therapeutic targets? [J]. Biomolecules, 2021, 11(11): 1716.

Gałęzowska G, Ratajczyk J, Wolska L. Determination of amino acids in human biological fluids by high-performance liquid chromatography: Critical review [J]. Amino Acids, 2021, 53(7): 993-1009.