School‐enterprise cooperation and work‐study combination are important measures for cultivating collaborative innovative talents under the background of new engineering education. Through in‐depth investigation of the current situation of school‐enterprise cooperation talents training, this paper analyzes the existing problems and reasons. Drawing on the experience of advanced collaborative innovation at home and abroad, according to the talent teaching mode in colleges and universities, relying on industrial development and the reality of new engineering education, an innovative scientific research platform and a production‐study‐research project are established to form a collaborative talent training mode with the integration of theory and practice, the integration of production and education, and the co‐construction and sharing of innovation centers. Practice shows that the deep combination of engineering training can effectively cultivate students application and innovation ability, and the good interaction between school and enterprise cooperation can also improve the innovation strength of enterprises.