Organic chemistry is an important component content in high school chemistry course, and the scattered and miscellaneous knowledge is also the prominent feature of this part of the content. This paper mainly studies the application of mind map in the teaching of organic chemical process. In this paper, teachers and students are trained in the study of mind mapping. The teaching of mind mapping is carried out by combining the preview and the specific lesson examples of new teaching. In the subject preview, students are prepared by combining the learning plan and drawing mind mapping independently. In the new class, the teacher guides the students to draw the mind map, which is combined with the class summary. The results show that students' academic performance has been significantly improved; Students' independent learning ability and cooperative learning ability have been improved to a certain extent, and students have obtained an effective learning method.