The Valladolid debate is an important event in the study of the process of conquest and colonization of Americans by the Spanish royal court. This debate reflected the two opposing views of the Spanish elites on Indians under the Christian framework, which involved whether the Spanish royal coon had a legitimate basis for conquering the Americans at that time. Thus, the Native Americans became the object of answering this question. This debate had not decided who was the winner or loser, and the tragic situation of the enslaved Indians would not be fundamentally improved. This debate is the concretization of the image of the American "other" constructed by Europeans and endowed the Spanish royal court with the meaning of legitimacy to conquer the Americas. Examining this debate from the perspective of the history of ideas, we can have a deeper understanding of the essence of Eurocentrism contained in the early European ideas of America.