- 期刊
Marjolin's Ulcer: A Case Report and Literature Review
摘要
Marjolin's ulcer is an aggressive cutaneous malignancy, which is common in previously traumatized or chronically inflamed skin. It has high regional metastasis and fatality rates. Our patient presented with ulcer, erythema, swelling and verrucous lesions on the left leg. He had a history of tibia fracture 30 years ago with poor wound heading. Histopathological examination of the excision specimen demonstrated well-differentiated/verrucous squamous cell carcinoma (SCC) with deep dermal invasion without lymph node metastasis. The patient received amputation after taking into consideration the deep dermal invasion and the possibility of local recurrence and distant metastasis. At 9-month follow-up, the patient had no relapse or metastasis. In this report, the etiology, diagnosis, treatment and prognosis of this disease are discussed with a brief review of the literature.