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Tubulocystic Renal Cell Carcinoma: A Rare Cystic Renal Neoplasm with Relatively Indolent Clinical Course

摘要


Tubulocystic renal cell carcinoma (TC-RCC) is a rare RCC subtype. Although it is categorized as a malignant tumor in current World Health Organization (WHO) tumor classification, TC-RCC presents clinically as a slowly progressing tumor, which is unusual compared to that of most other malignant renal neoplasms. Detailed pathogenic mechanisms of this tumor as well as genetic relationship between TC-RCC and the other RCC subtypes (especially papillary RCC) are not clearly understood. Here, we share a case of a 51-year-old Taiwanese male who came to our outpatient department with abnormal renal function and a complaint of hematuria. Imaging revealed a lesion at the upper pole of the left kidney. The patient subsequently underwent partial nephrectomy. Pathological examination revealed classical features of TC-RCC. No evidence of metastasis or recurrence was found during post-surgery clinical follow-up.

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