Urea-protein powder (UPP), made from urea by TLRI Hengchung Branch, was used to evaluate its effects on the blood urea nitrogen (BUN) concentration of goat. Decron bag techniques had been used for measuring the solubility of UPP in the water and the degradability of UPP inside the fistulated rumen of Holstein cattle. The result showed that UPP had lower solubility and degradability than that of urea in the water or rumen. On the urea tolerance experiments, eight castrated Nubian hybrid male kids were used to measure the toleration of BUN concentration on test goat. The ration contained 0%, 0.5%, 1% and 2% of UPP were used for deciding the suitable dosage of UPP in goat ration. The experiments last 30 days and the result showed that 2% of UPP can be used in the ration without affecting the physical activity and increased the BUN concentration of goats. Furthermore, ten castrated male Taiwan black goats and twelve Taiwan black doeling were fed with 2% of UPP ration for a day or 184 days long-term investigation. The results showed that there were no difference on BUN concentration for both goat and doeling in experimental and control groups. The UPP product can be used as a protein substitute for meat goat in a long period of time.