Formation pressure prediction is an important work in petroleum exploration and development. Accurate pressure prediction is an important guarantee for high-yielding and oil and gas sources. Formation pressure includes formation pore pressure, fracture pressure and collapse pressure. In order to ensure the safety of drilling and effectively release the potential of oil and gas reservoir, this paper combined with pre-drilling pressure prediction, drilling pressure monitoring and post-drilling pressure estimation, this paper explores how to improve the prediction accuracy of formation three pressure, and has achieved a series of innovative results. (1) A four step method of formation pore pressure prediction based on "regional law logging prediction actual measurement calibration comprehensive verification" is proposed to control the prediction error of formation pore pressure within 10%; (2) By combining the predicted and measured data, the critical value of formation fracture pressure in Dagang Oilfield is obtained, and the linear law of formation fracture pressure coefficient and vertical depth is determined (3) Based on the collapse theory research, borehole quality evaluation and formation three pressure relationship model, the rapid and accurate prediction of formation collapse pressure is realized. Finally, a set of formation pressure prediction and Optimization Countermeasures with reliable technology and strong operability are formed. In Dagang Oilfield, the incidence of drilling complications caused by formation pressure is zero in 2020.