18例血管角化瘤臨床病理分析

Clinicopathological analysis of 18 cases with angiokeratoma

古杰鳴(KU Kit Meng)

《鏡湖醫學》 20卷1期 (2020/06) Pp. 27-28+17+i

摘要

目的：分析血管角化瘤患者的臨床和組織病理特點。方法：對本院2008～2018年診治的18例血管角化瘤的臨床資料進行收集，應用HE染色進行病理學特徵觀察。結果：男10例，女8例，男：女比例為1.25:1，年齡13～79歲，平均45.9歲；病程1個月～2年，平均6.6個月，臨床以丘疹型及陰囊型多見。皮損組織病理檢查示：皮膚真皮層可見被表皮突包繞的毛細血管，毛細血管擴張伴充血，其表皮可見棘層增厚伴角化過度。治療以手術切除及鐳射治療。結論：血管角化瘤臨床表現多樣，分析其臨床特徵及組織病理學檢查，可加深臨床醫生及病理醫生對本病的認識並提高診斷的準確性。

關鍵字

血管角化瘤 ； 臨床特點 ； 病理學特點

並列摘要

Objective: To analyze the clinical characteristics and pathological features of patitents with angiokeratoma. Methods: During the period from 2008 to 2018, 18 cases with adult angiokeratoma were collected and analyzed using HE staining. Results: 18 cases with angiokeratoma, male 10 cases, female 8 cases, and the ratio of male to female was 1.25:1. The age of presentation was from 13 to 79 years old, and the mean age was 45.9 years old. The course of disease lasted from 1 month to 2 years, average 6.6 months. Clinically, the Mibelli type of angiokeratoma and Scrotal angiokeratioma are most common. Pathological examination of skin lesions revealed that angiokeratoma characteristically has large dilated capillaries in the papillary dermis with thickening of the stratum spinosum and hyperkeratosis, and the dilated capillaries are surround by the overlying epithelium. The treatments of angiokeratoma includes: direct surgical excision, and laser. Conclusion: The clinical manifestation of angiokeratoma is diverse. Analyzing its clinical characteristics and pathological features can help the clinician and pathologist to further understand angiokeratoma and improve the diagnostic accuracy.

並列關鍵字

Angiokeratoma ； Clinical characteristics ； Pathological features