- 期刊
- OpenAccess
澳門地區健康成人常規肺通氣功能測定及正常參考值範圍探討
A study of Macao reference values of spirometry parameters for non-smoking healthy adults
摘要
目的：探討澳門健康成人肺通氣功能特點，建立適合本澳健康成人的肺通氣功能預計值公式和正常參考值範圍。方法：2011～2012年通過宣傳招募到387例無吸煙史的本澳健康成年華人，通過詢問病史、行心電圖、胸片等檢查，最終362例符合條件納入研究。對362例納入者行肺通氣功能檢測，指標包括FEV1、FVC、FEV1/FVC等，將所得的實測值分別與年齡（A）、身高（H）、體重（W）等行相關分析，同時進行多元逐步線性回歸分析，得出預計值方程式；並與臨近地區預計值進行對比。結果：建立了華人的FEV1、FVC、FEV1/FVC的預計值公式；通過與其它地區預計值對比發現，FEV1%Pred，FVC%Pred的正常參考值≥80%，而FEV1/FVC%實測值的正常參考值≥72%，若取FEV1/FVC實測值佔預計值的百分比則女性≥84%，男性≥91%更適合本澳華人人群。結論：新建立的肺通氣功能預計值公式及正常參考值範圍更適合澳門人群，建議推廣應用。
並列摘要
Objective: To establish the predictive equations and reference values of spirometry parameters for Macao healthy adults. Methods: We measured spirometry with Jaeger Masterscreen instrument in healthy subjects (n=362; female 183, male 178) aged from18 to 78 years from January 2011 to December 2012. Multiple regressions and linear regressions were carried out with SPSS 17.0 to identify the best equations of spirometry parameters using height, weight, age as potential predictors. Results: Macao predictive normal equations and reference values were generated and compared with current published equations and reference values. When FEV1% Pred≥80%, FVC% Pred≥80%, EV1/FVC≥72%, (EV1/FVC)% Pred≥84% in female and≥91% in male, the false positive rates were the lowest. Conclusion: The newly developed predictive equations of spirometry parameters and reference value might be more suitable for Macao adults.