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皮脂腺痣5例臨床病理分析及文獻複習

Clinical pathological study and literature review of 5 cases of nevus sebaceous

摘要


目的:對5例皮脂腺痣的臨床病理分析及文獻複習。方法:5例皮脂腺痣採用常規HE染色,並分析其臨床病史及病理學特點。結果:3例(60%)出生時發病,男女之比為3:2。本病主要病理表現爲毛囊减少或缺失,可見成熟或接近成熟的皮脂腺小葉增生,部份皮脂腺直接與毛囊漏斗或表皮相通,皮脂腺小葉下方可見灶性大汗腺。結論:皮脂腺痣通常出生即可出現。最常發生於頭,頸部。組織學上皮脂腺可同時合併表皮,毛囊,皮脂腺和汗腺的異常,也可併發多種皮膚腫瘤。

關鍵字

皮脂腺痣 鑒別診斷

並列摘要


Objective: To evaluate the clinicopathological features and literature review of Nevus Sebaceous. Methods: 5 cases of Nevus Sebaceous were investigated by hematoxylin-eosin, the clinical history and pathlogical features were analyzed. Results: In 3 cases (60%) nevus sebaceous occurred during birth, male and female proportion was 3:2. The main pathological features were decreased or disappeared of hair follicles, mature or near mature sebaceous gland hyperplasia were seen, parts of sebaceous gland were directly communicated with follicular infundibulum or epidermis, focal apocrine gland were present below the sebaceous glands. Conclusion: Nevus Sebaceous often presents at birth and commonly affects the head and neck area. Nevus sebaceous is complex lesion comprising abnormalities of the epidermis, hair follicles, sebaceous and sweat glands, and frequently complicated by development of various other cutaneous neoplanms.

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