- 期刊
Alveolar Ridge Preservation with the Open Barrier Membrane Technique Using Freeze Dried Bone Allograft and Non-resorbable Membrane: Long-term Clinical and Histomorphometric Results
摘要
Alveolar ridge preservation (ARP) can reduce alveolar ridge resorption following tooth extraction and facilitate restoration-driven implant placement. Freeze-dried bone allograft (FDBA) serves as an osteoconductive scaffold in such procedures, promoting bone regeneration. In this clinical study, we analyzed the histological findings and clinical outcomes of ARP performed using the open barrier membrane technique with FDBA and a high-density polytetrafluoroethylene (d-PTFE) membrane. Methods: This study included six patients who had undergone ARP with FDBA and a d-PTFE nonresorbable membrane without primary closure. After healing (for at least 6 months), dental implants were placed and biopsy specimens were collected concurrently. Clinical outcomes and histological findings, including the percentages of newly formed bone structures, residual graft particles, and fibrous connective tissue, were analyzed. Results: All six patients exhibited successful osseointegration and loading of the implants, with no need for additional guided bone regeneration surgery or soft tissue grafting during post-ARP implant placement. Histologically, the percentages (presented in terms of mean ± standard deviation values) of newly formed bone structures, residual graft particles, and fibrous connective tissue were 32.6% ± 19.2%, 41.4% ± 19.4%, and 27.8% ± 14.9%, respectively. Voids in histological images were excluded from these calculations. Conclusion: This study indicates that ARP performed using the open barrier membrane technique with FDBA and a d-PTFE membrane is a viable method for preserving the dental ridge before placing dental implants. Further long-term research on the use of these materials in ridge preservation is necessary.