研究背景:無規律運動且長時間久坐者有較高機會罹患高血壓,增加心血管疾病風險,然而中斷久坐是否能影響血壓目前仍不清楚,也缺乏不同族群的比較。方法:本研究招募無規律運動習慣的健康成年人,針對體重正常(研究1:10人,年齡:25±4,BMI:21±2kg/m^2,腰圍:73±6cm)和體重過重(研究2:12人,年齡:29±7,BMI:29±5kg/m^2,腰圍:97±6cm)族群進行久坐(實驗期間維持坐姿)和中斷久坐(每20分鐘進行時速6.4公里的2分鐘快走,總計30分鐘)實驗,實驗總長度為320分鐘,並採隨機次序分配。血壓(收縮壓、舒張壓及平均動脈壓)於餐後每小時測量,共6次(基礎值、第65、125、185、255和315分鐘),並以2因子重複量數變異數分析檢驗不同介入與時間的差異,顯著水準為p<0.05。結果:研究1和研究2結果皆顯示久坐與中斷久坐間收縮壓、舒張壓及平均動脈壓均無顯著差異。結論:不論體重正常或體重過重族群,中斷久坐的身體活動皆未能立即性降低血壓。
Introduction: Daily irregular physical activity and prolonged sitting are associated with a higher risk of developing hypertension and cardiovascular diseases. However, it is currently unclear whether breaking prolonged sitting can affect postprandial blood pressure, and there is a lack of comparison among different populations. Methods: Healthy adults without regular exercise habit were recruited and divided into study 1: normal weight group (N=10, age: 25 ± 4, BMI: 21 ± 2 kg/m^2, waist circumference: 73 ± 6 cm), and study 2: overweight group (N=12, age: 29 ± 7, BMI: 29 ± 5 kg/m, waist circumference: 97 ± 6 cm). Participants underwent prolonged sitting (maintaining a sitting position throughout the experiment) and breaking up prolonged sitting (walking on a treadmill at a speed of 6.4 km/h for 2 minutes every 20 minutes, total of 30 minutes of brisk walking). Blood pressure (systolic, diastolic, and mean arterial pressure) was measured at baseline, 65, 125, 185, 255, and 315 minutes during the experiment. Results: The results of study 1 and study 2 both showed no significant differences in systolic, diastolic, and mean arterial pressure between prolonged sitting and breaking up prolonged sitting. Conclusion: Breaking up prolonged sitting with intermittent short bouts of physical activity, regardless of normal weight or overweight/obese, did not immediately lower blood pressure.