一套新穎的應用混合實境裝置進行眼振偵測之臨床系統

A Novel Nystagmus Detection System Using A Mixed Reality Headset

林則瀚(Tse-Han Lin)

指導教授 ： 歐陽明 ； 陳文進 ； 楊庭華

國立臺灣大學/電機資訊學院/資訊工程學研究所/碩士(2021年)

https://doi.org/10.6342/NTU202101346

摘要

我們提出使用混合實境裝置，Microsoft®HoloLens2，來進行眼振檢測的測試。這個產品與現今使用的檢測工具，如影像眼震檢查儀及眼振檢查鏡相比，具有許多優點。我們設計了方便使用的使用者介面來展示測試中經過濾波後的眼睛移動波形圖。其中眼振是經由法則式的演算法從波形中檢測出。在實驗室中，我們去和眼振偵測的標竿，影像眼震檢查儀比較，而其結果及準確度和影像眼震檢查儀相近。另外，我們的產品目前正在診間對具有暈眩問題的病患進行臨床實驗。在實驗一中，我們藉由與影像眼震分析檢查儀記錄的結果比較來驗證裝置的正確性。至於眼振偵測演算法，則是由視動性眼球震顫測試的波形作為典型眼振波形來參考驗證，並由一位專精於暈眩的耳科醫生認證其效力。在實驗二中，我們透過直接對具有暈眩問題的病患進行臨床實驗HoloLens2TM在臨床檢測中的使用，並與耳鼻喉科醫師使用眼振檢查鏡之結果相比較。結論顯示了在臨床測試中使用我們在HoloLens2TM中設計的產品來測試是非常有可行性的。而整個系統，包括實驗設計、驗證的方式等，可以在經過適當的改動後移植到其他的裝置。

關鍵字

眼振偵測 ； 混合實境裝置 ； HoloLens2 ； 溫差實驗 ； 視動性眼振測 ； Dix-Hallpike測試 ； 良性陣發姿勢性眩暈 ； 影像眼震分析檢查儀

並列摘要

We propose the use of a mixed reality headset, Microsoft®HoloLens2TM to perform nystagmus diagnostic tests. This product has many advantages over current diagnostic tools, e.g., videonystagmography (VNG) device, Frenzel glasses, etc. A friendly user interface was designed to show the filtered waveform of the eye movement during the tests. The nystagmus pattern is detected from the waveform by a rule-based method. In the laboratory, our product has been compared with VNG, the benchmark device of nystagmus detection, and the results and accuracy were comparable in both devices. Furthermore, our product is currently undergoing clinical experiment on patients presenting vertigo/dizziness in clinic.In experiment 1, we validate the product's accuracy with the VNG device. As for detection algorithm of nystagmus, optokinetic nystagmus (OKN) was utilized as a reference for the pattern of vestibular nystagmus, and the eligibility was approved by an otologist specialized in vertigo/dizziness. In experiment 2, we validate the use of HoloLens2TM to perform the clinical test of nystagmus directly in patients presenting vertigo/dizziness, and the results were compared with those done by the ENT doctors using Frenzel glasses. The conclusion indicates that the product we built in the Hololens2TM is promising in the clinical testing of nystagmus. The whole system, experimental design, and validation methods can be ported to other similar devices if proper modified.

並列關鍵字

nystagmus detection ； mixed reality headset ； HoloLens2 ； caloric test ； optokinetic nystagmus ； Dix-Hallpike test ； BPPV ； videonystagmography (VNG)

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