After sterilization process or long term storage, fish and meat packaging food which contains biochemistry protein do easily cause black discoloration problem on interior packaging coating of can container. This research aims at solving the black discoloration problem by optimizing the resin formulation of epoxy, phenolic and amino resins, the selected resins must have a reliable supply source and meet the national health and food regulation. We evaluate different properties of the coating. This study provided an understanding to the formulations for real application. We expect this study will become the basic guidelines of high quality packaging coating for fish and meat food can container. This study will not only promote the quality of current packaging coating but also meet the critical requirements of the Safety & Hygiene regulation.