- 學位論文
孕婦鈣質攝取對健康足月新生兒骨質之影響
The effect of calcium intake during pregnancy on bone mass in healthy full term newborn infants
摘要
本研究目的在於探討孕婦在懷孕期間鈣質的攝取對健康的足月新生兒骨質密度(Bone Mineral Density, BMD)所造成的影響。共144位孕婦及新生兒參與研究。以量化超音波骨聲速度(quantitative ultrasound measurement of bone speed of sound, SOS)評估高雄醫學大學附屬紀念中和醫院之新生兒的骨質數值，並紀錄相關基本資料包括新生兒的出生身高、體重、頭圍和出生後一分鐘和五分鐘的Apgar score。孕婦的鈣質攝取則以半定量飲食頻率問卷(Semi Food Frequency Questionnaires, SFFQ)計算出鈣質攝取量，最後以JMP統計軟體分析數據之相關性。結果發現新生兒骨質SOS的平均值為2960.76 m/s (SD: 102.06 m/s)，孕產婦在懷孕期間鈣質攝取平均值為753.52 mg/day (SD: 361.03 mg/day)，而兩項數值具有相關性( P=0.0232)。藉由研究結果可以提供健康足月新生兒SOS骨質數據並對於懷孕期婦女補充鈣質給予飲食建議，顯示懷孕期間適度的鈣質攝取及補充對新生兒的骨質生長是有助益的。
並列摘要
The fetal skeleton and postnatal bone growth may be affected by maternal intake during pregnancy. The purpose of this study is to determine the effect of maternal calcium intake during pregnancy on bone mass measured with speed of sound (SOS) in 144 healthy full term newborn infants. Healthy without resuscitation term infants who are admitted to baby room of Kaohsiung Medical University Hospital will be enrolled. We used the Semi Food Frequency Questionnaires (SFFQ) to evaluate the status of maternal calcium intake during pregnancy after agreement. SOS measured by quantitative ultrasonography will be performed at the left tibia in one week after birth. The association between maternal calcium intake during pregnancy and bone growth assessed by SOS in health term infants will be analyzed by statistic methods. The mean SOS in these infant were 2960.76 m/s (SD: 102.06 m/s). Mathernal calcium intake during pregnancy was 753.52 mg/day (SD: 361.03 mg/day). The statistics showed there was significant correlation between SOS and total calcium intake during pregnancy ( P=0.232). Our data provide information about the appropriate diet suggestion about calcium intake and supplement for pregnant mother and bone growth pattern in health term infants.