The object of this research is trying to focus on the relationship between the Volatility Index, Business Cycle and stock price return. We chose three major indictors of the U.S. stock market, S&P500、NASDAQ and DJIA. According to the Business Cycle constructed by NBER, we used the ICAPM model to examine VIX and return. Try to find the regression model is positive or negative. The empirical results show that there is a significant positive relationship between expected returns and VIX in the long term when the economy recession. However, there is a significant negative relationship between expected return in economy expansion, also the three indicators give consistent results.