- 學位論文
快速動眼睡眠剝奪對錯誤監控之影響
Effects of Rapid Eye Movement Sleep Deprivation on Error Monitoring
摘要
本研究透過快速動眼睡眠(Rapid-eye-movement sleep,以下簡稱REMS)剝奪的操弄，試圖瞭解REMS在錯誤監控運作上所扮演的角色。本研究共收集10位研究參與者(其中6位為女性，年齡20至22歲)的睡眠、認知作業行為表現和事件相關腦電位(event-related brain potential, ERP)等資料。每位研究參與者皆接受三個實驗期的測量，包括維持日常作息的基準期(baseline)、剝奪REMS (RD)及共軛控制(YC)情境；並於接受睡眠操弄夜晚後的隔天早上，進行箭頭版的旁側夾擊作業，以及同時收集腦波(electroencephalogram, EEG)訊號。RD及YC睡眠操弄皆造成睡眠結構的改變且兩種操弄間也呈現睡眠變化差異，後者包括： RD夜晚的整體睡眠時間與REMS皆較YC夜晚少；RD夜晚的睡眠第一期總量、睡眠轉換總量和整夜睡眠覺醒指數、REMS覺醒指數等皆顯著多於YC夜晚。然而，主觀報告的睏睡度、認知作業的整體行為表現、及ERP等資料皆未呈現RD和YC操弄的差異。和基準期相較，RD和YC操弄也未改變認知作業的行為表現，但RD和YC的ERN振幅顯著低於基準期。本研究結果顯示無論是REMS或部份睡眠剝奪皆可能造成錯誤監控運作的弱化，但並未支持REMS剝奪對於錯誤監控系統的運作有不同於其他睡眠階段的影響。
並列摘要
The main purpose of this study is to explore the role of rapid-eye movement (REM) sleep on error monitoring by REM sleep deprivation. Ten participants (6 females, age: 20-22 years) each underwent 3 sleep conditions, including baseline (maintaining regular sleep schedules), RD (REM sleep deprivation), and YC (yoke control). Flanker task performance and electroencephalogram data were collected in the morning following the baseline sleep, RD, and YC nights. Compared to the adaptation night before sleep manipulations, both RD and YC nights led to changes in sleep stage distribution. Compared to the YC night, the RD night had reduced the total sleep time and REM sleep time; and increased the N1 sleep time, number of sleep stage changes, total arousal index, and REM sleep arousal index. The ERP data indicate that compared to baseline, the mean amplitude of ERN at FCz was reduced in both the RD and YC conditions. Subjective evaluations on sleepiness and the Flanker task performance did not differ between the 3 sleep conditions. Compared to the baseline condition, both RD and YC resulted in smaller amplitudes of the error-related negativity (ERN). This study showed that partial sleep deprivation weakened error detection but failed to support a specific effect of REM sleep on error monitoring.