- 學位論文
中年人肌少症與骨質疏鬆症之相關因素探討
Factors Associated with Sarcopenia and Osteoporosis in Middle-aged Adults
摘要
背景與目的：生命餘命增加，中年人健康受到重視，故本研究探討中年社會人口學特性、肌少症指標與骨質疏鬆症相關性。 研究方法：本研究屬於次級資料之相關性研究設計，利用南部某集團醫院2018年8月1日至2021年3月31日期間(共30月)自費健康檢查資料。統計分析方法為描述資料與推論性分析，探討肌少症與骨質疏鬆症的盛行率與相關因素。 結果：資料包含50至65歲的中年人共1033人，平均年齡57.06歲(±4.31)，男性590人(57.1%)，女性443人(42.9%)。肌少症的指標有手握力、行走速度、肌肉量。手握力低158位(15.3%)，行走速度慢561位(54.3%)，肌肉量低594位(57.5%)。符合三項指標的肌少症有359位(34.8%)，年盛行率為13.9%。羅吉斯迴歸結果顯示肌少症危險因素有年齡增加與低BMI。骨質疏鬆症有150位(14.5%)，年盛行率5.8%；骨質疏鬆症相關的危險因素：年齡、女性、低BMI、無吸菸、無飲酒、無飲用咖啡、無飲用茶、無維生素D攝取、低咖啡攝取量、低茶攝取量、少吸菸量、少飲酒量、少日曬時間與低手握力。羅吉斯迴歸結果顯示骨質疏鬆症危險因素有年齡增加、女性、低BMI與日曬時間少。 結論：自費健檢的中年人的肌少症與骨質疏鬆症的比例相對高，年齡與BMI是重要相關因素；年齡增加與BMI減少，反而會增加肌少症與骨質疏鬆症的暴露。
並列摘要
Background and Objectives: Attention is paid to middle-aged people for their health condition as the increasing of life expectancies. Therefore, this study was aimed to examine factors of sociodemographic characteristics related to sarcopenia and osteoporosis middle-aged people. Research Methods: This study was a cross-sectional design using secondary data of out-of-pocket health examination reports between August 1, 2018 to March 31, 2021 (a total of 30 months) from a group of hospitals in southern Taiwan. Statistical analyses included descriptive and multivariate analyses to assess the prevalence of sarcopenia and osteoporosis and relevant factors. Results: There were 1033 middle-aged people aged 50 to 65 included in the analysis; of them, the mean age was 57.06 years (±4.31), 590 were males (57.1%) and 443 were females (42.9%). Three indicators, i.e., grip strength, walking speed, and muscle mass, are used to assess the condition of sarcopenia. There were 158 people (15.3%) with low hand grip strength, 561 (54.3%) with slow walking speed, and 594 (57.5%) with low muscle mass. There were 359 people (34.8%) met the criteria of sarcopenia, resulting the prevalence was 13.9%. Results of logistic regression showed that an increase of age and low body mass index (BMI) were associated with the increasing of likelihood of sarcopenia. There were 150 people (14.5%) met the criteria of osteoporosis with the prevalence 5.8%. Factors associated with osteoporosis were age, female, low BMI, no smoking, no drinking, no coffee intake, no tea intake, no vitamin D intake, low volume of coffee intake, low volume of tea intake, low amount of cigarettes usage, low amount of alcohol consumption, low exposure to sun-light, and low hand grip strength. Results of logistic regression showed that factors associated with osteoporosis were increasing of age, female, low levels of BMI and less exposure of sun-light. Conclusions: The percentage of sarcopenia and osteoporosis in middle-aged people who used out-of-pocket health examinations is considered high. Key factors were age and BMI; increasing age and decreasing BMI were more likely to increase the possibility of sarcopenia and osteoporosis.