金箔應用在人肝癌模式動物之效果評估

Anti-cancer Effect of "Jin Bo-Native Gold " on Human Hepatic Tumor Cell Line (SMMU-7221) in SCID Mice

蔡金川(C. C.Tsai) ； 賴東淵(T. Y. Lai) ； 呂明進(M. C. Lu) ； 陳悅生(Y. H. Chen) ； 林昭庚(J. G. Lin) ； 吳銘芳(M. F. Wu)

《臺灣中醫醫學雜誌》 2卷1期 (2003/03) Pp. 55-61

摘要

肝癌是國人甚至亞洲地區最主要的癌症死因之一，目前尚無有效的治療藥物。我們將探討金箔是否有益於人體，了解金箔之抗癌效果。我們以人肝癌細胞（Smmu 7721細胞株）3× 107個細胞0.5cc接種於SCID mice背部皮下作成肝癌模式動物，侍腫腫瘤長至0.25~0.35cm時，以金箔作口服治療（3.6mg/day），連續觀察五週後，安樂死部檢觀察。結果發現，以金箔做治療之與對照組相比較，其腫瘤似有呈緩慢生長。並且提高老鼠對臟轉移細胞B16細胞注射的存活率。

關鍵字

金箔 ； 人肝癌細胞 ； 抗癌 ； 肺臟轉移細胞B16 ； 存活率

並列摘要

Liver cancer is one of the major causes of cancer death in Taiwan as well as in China. Until now, there is no effective treatment in it. In the present study, we not only investigated the advantage of Jin Bo-native gold for human health but also studied its anti-cancer effect. We inoculated human hepatic tumor cell lines of SMMU-7221(3×107cells per 0.5cc) into the dorsal subcutaneous tissue in SCID mice. When the tumor mass was greater than 0.25~0.35cm, we treated the mice with native gold (3.6mg/day) by P.O. All animals were continuously observed for five weeks, and then sacrificed for anatomic obseration. As a result, tumor in the mice treated with native gold apparently grew slower than that in the normal control group.

並列關鍵字

Jin Bo (Native gold) ； human hepatic tumor cell line ； anti-cancer