銀杏葉萃取物(EGb761)對東莨菪鹼誘發小鼠學習獲得障礙之影響

Influence of Ginkgo Biloba Extract (EGb761) on the Learning Obstacle of Mouse Induced by Scopolamine

梁健成(Jian-Cheng Liang) ； 王銘富(Ming-Fu Wang) ； 黃克峯(Keh-Fong Hwang)

《傳統醫學雜誌》 19卷1期 (2008/04) Pp. 117-122

https://doi.org/10.30038/JTM.200804.0012

摘要

銀杏葉萃取物(Ginkgo biloba extract; EGb761)主要是用來改善周邊循環作用，近年來有文獻報導長期使用有增強認知功能與清除體內自由基的作用，本實驗主要是探討連續口服給與小鼠銀杏葉卒取物兩星期後並用東莨菪鹼(Scopolamine)來誘發小鼠學習獲得之障礙，結果得知銀杏葉萃取物可以改善東莨菪鹼誘發小鼠學習獲得障礙，即銀杏葉萃取物可以改善小鼠之學習記億能力。

關鍵字

銀杏葉萃取物 ； 東莨菪鹼 ； 學習記憶

並列摘要

The Ginkgo biloba extract (EGb761) is mainly used to improve the function of peripheral circulation. In recent years, some literatures report that it can strengthen the cognitive function and remove the free radical from body after taking it for a long time. The main purpose of this experiment is to study the learning obstacle of mouse induced by Scopolamine after taking Ginkgo biloba extract for two weeks. The result show that the Ginkgo biloba extract can improve the learning obstacle of mouse induced by Scopolamine, which means the Ginkgo biloba extract can improve the learning memory of mouse.

並列關鍵字

Ginkgo biloba extract ； Scopolamine ； learning memory