Menstruation is one physical characteristic of women. But, many women suffer from dysmenorrhea (menstrual pain). In the western medicine, dysmenorrhea is typically treated with medicine such as hormone and analgesics. It has been showed that chronic use of these drugs treating inflamrnatory disorders is associated with significant adverse effects. As one of the most used Chinese herbal medicines in treatment of dysmenorrhea, Chinese angelica is famous for its functions of activating blooding, relieving pain, regulating menstruation and engendering blood. With the combination of the theory of traditional Chinese medicine and aromatherapy, this Company used Chinese agelica as the major ingredient and successfully developed the compound essential oil MA3B. The in vitro and in vivo experiments showed that MA3B can effectively inhibit the contraction of rat uterine smooth muscles and ease dysmenorrhea of the rat. Through inhibiting platelet activation, increasing erythrocytes counts and hemoglobin concentration, MA3B with good stability has improvement of the blood counts and the function of engendering blood. Our compound essential oil MA3B is helpful to relieve the menstruation period ill symptom.