According to the syndrome differentiation of Chinese medicine, the occurrence of constipation is caused by pathogenic heat, deficiency of Yang, stagnation of Qi, deficiency of Qi and blood, and wind evil. The patients with more symptoms of deficiency of Yang or deficiency of Qi and blood are diagnosed as the pattern of spleen vacuity weakness. Using cold purgative formula for the treatment of constipation with symptoms of Yang deficiency is erroneous. A case with spleen-kidney yang vacuity was treated with warm purgative formula and got beneficent therapeutic effects. With this case study, we try to offer a new direction for discussion.