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山楂萃取物抗氧化活性與對PC12細胞生長之影響

Antioxidant Activity and Effect on PC12 Cell Growth of Crataegus Pinnatifida Extracts

摘要


山楂主要用於促進消化,近年來有文獻報導山楂萃取物能清除自由基,本研究主要是探討山楂萃取物清除1, 1-diphenyl-2-picrylhydrazyl (DPPH)自由基的能力及對PC12細胞生長的影響,結果得知山楂甲醇萃取物清除DPPH自由基的能力最佳,可以促進PC12細胞生長,具有在食品與醫藥上應用於神經退化性疾病開發的潛力。

並列摘要


Crataegus pinnatifida is used mainly for promoting digestion. In recent years, some literatures report that Cretaceous pinnatifida extracts can remove the free radicals. The research is mainly to probe into the scavenging capacity of the l, l-diphenyl-2-picrylhydrazyl (DPPH) radicals and the influence on PC12 cell growth for the Crataegus pinnatifida extracts. The results show that the methanolic extract of the Crataegus pinnatifida had the best scavenging capacity of the DPPH radicals. The methanolic extract of the Crataegus pinnatifida can promote PC12 cells to grow, and it possesses the application and exploitation of the neurodegenerative disease for the food and medicine.

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