青蒿鱉甲湯合牡蠣散加減治療淋巴癌睡眠嚴重盜汗之醫案報告

Modified Qing Hao Bie Jia Tang and Mu Li San in the Treatment of Malignant Lymphoma with Severe Night Sweats: A Case Report

呂秉勳(Ping-Hsun Lu) ； 楊淑君(Shu-Chun Yang) ； 林宜信(I Hsin Lin)

《中醫藥研究論叢》 26卷1期 (2023/03) Pp. 69-80

https://doi.org/10.6516/TJTCM.202303_26(1).0006

摘要

淋巴瘤的發生率逐年提升，死亡率已上升至第九位。西醫針對淋巴癌主要以化學治療為主，針對B細胞淋巴瘤的病人還可選用標靶藥物Rituximab治療，當淋巴癌大於10公分或有某些局部侵犯時可考慮合併局部放射治療。B症候群如夜間盜汗、發燒與體重減輕為淋巴瘤患者常見之症狀，然而西醫對於此症狀之緩解較無著墨，但是淋巴癌B症狀的嚴重度著實影響了病患的生活品質與預後。此篇案例報告一位因淋巴癌發燒及睡眠嚴重盜汗，一晚需更換八套衣服與床單，眠差影響體力與生活品質的病人，在服用青蒿鱉甲湯合牡蠣散加減一周後發燒與盜汗症狀完全改善並得以繼續進行化療的顯效案例。

關鍵字

淋巴癌 ； 淋巴癌B症狀 ； 睡眠盜汗 ； 青蒿鱉甲湯 ； 牡蠣散

並列摘要

The incidence of lymphoma is gradually increasing year by year, and the mortality rate has risen to the ninth place. Western medicine mainly focuses on chemotherapy for lymphoma. Patients with B-cell lymphoma can also choose the targeted drug Rituximab for treatment. When the lymphoma is larger than 10 cm or has some local invasion, local radiotherapy can be considered. However, Western medicine has little to do with the relief of common B symptoms of lymphoma, such as fever, night sweats, and weight loss, but the severity of lymphoma B symptoms does affect the quality of life and prognosis of patients. This case reports a patient who had a fever and severe night sweats during sleep due to lymphoma cancer. He had to change 8 sets of clothes and sheets in one night. Poor sleep affected his stamina and quality of life. After taking modified Qing Hao Bie Jia Tang and Mu Li San for a week, the symptoms of fever and night sweats completely improved, and chemotherapy can be continued.

並列關鍵字

Lymphoma ； lymphoma B symptoms ； night sweats ； Qing Hao Bie Jia Tang ； Mu Li San

參考文獻

Li X, Qin XM, Tian JS, Gao XX, Du GH, Zhou YZ. Integrated network pharmacology and metabolomics to dissect the combination mechanisms of Bupleurum chinense DC-Paeonia lactiflora Pall herb pair for treating depression. J Ethnopharmacol. 2021; 264: 113281.

Swerdlow SH, Campo E, Pileri SA, Harris NL, Stein H, Siebert R, et al. The 2016 revision of the World Health Organization classification of lymphoid neoplasms. Blood. 2016; 127(20): 2375-90.

Cazzola M. Introduction to a review series: the 2016 revision of the WHO classification of tumors of hematopoietic and lymphoid tissues. Blood. 2016; 127(20): 2361-4.

Hallek M, Cheson BD, Catovsky D, Caligaris-Cappio F, Dighiero G, Dohner H, et al. Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines. Blood. 2008; 111(12): 5446-56.

王茂生、李君、孫長勇、周玉才：楊淑蓮教授治療淋巴瘤經驗。河北中醫2016；(1)：8-11。