This is a 47-year-old male patient. He worked in China for many years and had been diagnosed with liver cirrhosis. He did not receive regular medical treatment, and kept drinking. After he came back to Taiwan, he suffered from nausea, coffee-ground vomitus, fever, severe jaundice, leg pitting edema, ascites and melena, so he came to our hospital for emergency treatment. His renal function deteriorated during hospitalization, and hepatorenal syndrome was suspected. Then, the patient asked his doctor for Chinese medicine treatment. After nearly two weeks of treatment and follow-up, his renal function significantly ameliorated. He was discharged from our hospital. We demonstrated the experience of integrated therapy of Traditional Chinese Medicine and Western Medicine in this case report as the reference and application in clinical treatment.